Feature

New breath test could detect heart disease in dogs earlier

A mask is placed over a dog's face while its breath is analyzed as part of a research study at the Veterinary Medical Center.

Imagine if a single breath could tell your veterinarian exactly what is happening inside your dog’s heart. 

For many pet owners, heart disease is a "silent" threat, often ranked as the second leading cause of mortality in dogs. Because dogs are experts at hiding discomfort, many don’t show symptoms until they are in the midst of a life-threatening emergency. By the time a dog is struggling to breathe, the disease has often progressed to congestive heart failure, requiring expensive ICU stays and intensive oxygen therapy.

Christopher Stauthammer, professor of cardiology at the University of Minnesota College of Veterinary Medicine and a specialist at the Veterinary Medical Center, is working to change that narrative. His research focuses on catching heart disease long before it reaches a crisis point. 

"Detecting congestive heart failure is exceptionally challenging in a primary care clinic and is often missed," Stauthammer says. "When we can detect heart failure sooner, we can save more lives and prevent the progression of underlying heart disease and complications."

To bridge this diagnostic gap, the cardiology team partnered with a medical device company to develop and test a revolutionary bedside breath analyzer. The device uses a specialized interface — resembling the small oxygen masks seen on airplanes — to capture exhaled air. Inside the device, high-tech biosensors analyze volatile organic compounds, which are metabolic byproducts that travel from the blood into the lungs. By measuring these "breath signatures," the team can identify specific patterns that distinguish a healthy dog from one with underlying heart disease or active heart failure.

The results from initial pilot projects have been remarkably promising. Stauthammer’s team found they could successfully detect differences in the breath profiles of healthy dogs versus those with various stages of heart disease. These findings suggest the device could be a game-changer.

Now, the research is moving into its next critical phase: a new trial involving dogs arriving at emergency clinics in respiratory distress. The ultimate goal is to place these breath analyzers in the hands of primary care veterinarians everywhere. By making heart disease detection as simple as a bedside breath test, providers can guide treatment decisions earlier and provide owners with a clearer prognosis without the immediate need for expensive, specialized imaging. While the current focus is on dogs, the long-term vision includes expanding this technology to cats and other companion animals.

For Stauthammer, the technology is exciting, but the real advancement lies in the time it buys for families and their pets. By turning a routine breath into a diagnostic powerhouse, he is helping to ensure that a diagnosis doesn't have to be an emergency, and that more dogs can enjoy a high quality of life for years to come.