Mark Osborn

Introduction

Dr. Mark J. Osborn, P.h.D., is an associate professor in the Department of Pediatrics, Division of Blood and Marrow Transplantation, at the University of Minnesota Medical School.

Osborn’s current research is focused on gene and cellular therapy for disorders treated by hematopoietic cell transplantation, including: Fanconi anemia, epidermolysis bullosa, and Hurler syndrome. This involves utilizing a patient’s own cells for precision gene targeting and correction of their disease-causing mutation. Genome-editing nucleases and multiple terminally differentiated and stem cell populations are utilized toward optimizing ex vivo cellular therapies.